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Tirzepatide

Price range: $75.00 through $360.00

What is tirzepatide?

Tirzepatide (Zepbound brand) is used for weight loss, to help lose weight and keep weight off. Tirzepatide works for weight loss by decreasing appetite and slowing the movement of food from the stomach into the small intestine, which may make you feel full more quickly and for a longer period. The Zepbound brand of tirzepatide is also used for moderate to severe obstructive sleep apnea (OSA) in adults with obesity. Tirzepatide is a once-weekly injection given under the skin using a pen (autoinjector).

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How does tirzepatide work?

Normally, when we eat, natural hormones called GIP and GLP-1 are released by the gut. These hormones increase insulin release, suppress appetite, slow gastric emptying, and increase the feeling of fullness. Tirzepatide works like our natural hormones GIP and GLP-1 by activating the GIP and GLP-1 receptors.

Tirzepatide is a GIP and GLP-1 receptor agonist.

Tirzepatide works (mechanism of action) by activating both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors.

Before using tirzepatide

Tell your doctor and pharmacist if you are allergic to tirzepatide, any other medications, or any of the ingredients in this medicine. There is a list of ingredients in this medicine, at the bottom of this page.
Tell your healthcare team if you are planning surgery or other procedure that uses anesthesia or deep sedation.
Tell your doctor if you have or have ever had kidney or pancreas disease, a history of diabetic retinopathy or any stomach problems such as difficulty digesting food.
Tell your doctor if you plan to become pregnant, are pregnant, or are breastfeeding. If you become pregnant while taking this medicine, you should tell your doctor.

How should I use tirzepatide?

You should follow the directions on your prescription label carefully and ask your pharmacist or doctor to explain any part you do not understand. It is important to use this medicine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Tirzepatide is injected under the skin (subcutaneously) using a pre-filled pen or a single-dose vial with a syringe. Caregivers or patients should be trained on proper injection techniques. When using single-dose vials, a 1 mL syringe capable of measuring a 0.5 mL dose must be used for dose administration.

t is usually given

once a week.
can be given with or without meals at any time of the day.
may be injected into the thigh, abdomen, or upper arm.
You should rotate injection sites with each dose.

Your doctor will probably start you on a low dose, which may be gradually increased, but not more than once every 4 weeks.

You may change the day of the week you use tirzepatide as long as there are at least three days between doses.

You may administer insulin in the same area as tirzepatide, but they should not be given right next to each other. Insulin and tirzepatide should be given as separate injections and not be mixed in the same injection.

Mounjaro controls type 2 diabetes but does not cure it. It may take four weeks or longer before you see the full benefit of this medicine. Continue to take this medicine even if you feel well. Do not stop taking this medicine without talking to your doctor.

Warnings

Tirzepatide may cause thyroid C-cell tumors. It is important to tell your doctor if you have a personal or your family has a history of thyroid cancer or a condition called Multiple Endocrine Neoplasia (MEN) syndrome. This is a syndrome that causes tumors to develop on endocrine glands. If you experience any of these symptoms: lump or swelling in your neck, difficulty in swallowing, hoarseness, or shortness of breath, then you should call your doctor immediately.